MiT/TFE Family of Transcription Factors, Lysosomes, and Cancer
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چکیده
منابع مشابه
MarR family transcription factors
Figure 1. Representative MarR homologs and their mode of gene regulation. (A) Structure of MTH313 (3BPX), a MarR homolog of unknown function from Methanobacterium thermoautotrophicum, in complex with the ligand salicylate (shown in magenta). One monomer is shown in gray, the other is colored from amino to carboxyl terminus (blue to red). Note the asymmetrical ligand binding; only ligand binding...
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CudA, a nuclear protein required for Dictyostelium prespore-specific gene expression, binds in vivo to the promoter of the cotC prespore gene. A 14 nucleotide region of the cotC promoter binds CudA in vitro and ECudA, an Entamoeba CudA homologue, also binds to this site. The CudA and ECudA DNA-binding sites contain a dyad and, consistent with a symmetrical binding site, CudA forms a homodimer i...
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ژورنال
عنوان ژورنال: Annual Review of Cancer Biology
سال: 2019
ISSN: 2472-3428,2472-3428
DOI: 10.1146/annurev-cancerbio-030518-055835